Biotechnology - Equipment
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Equipment |
The Unit Biotechnology has of the following facilities:
- Pilot plant
- Laboratory for molecular biology (withISO17025 accreditation)
- Laboratory for mammaliancell culture
- Pilot plant for downstream processing (DSP) andbioanalytics
Our labs and pilot plants feature the following equipments:
Microbial bioprocess development
- Multifermenter with 4 units of 0.5 L (Sixfors, Infors AG)
- Lab scale bioreactors
- 2.5 L – with regulation IMCS-2000 (newMBR AG)
- 3.6 L (Labfors, Infors AG)
- 3.7 L (KLF2000, Bioengineering AG)
- 20 L – with regulation IMCS-2000 (newMBR AG)
- Pilot bioreactors 42 L, 50 L, 300 L (Bioengineering AG)
Downstream processing (DSP)
- Dyno Mill KDL bead mill
- Äkta Explorer for preparative chromatography
- Branson S450 Sonifier
- Micro- and ultrafiltration equipments (bench and pilot scale)
- Centrifuges (bench and pilot scale)
- UpFront and Streamline expanded bed adsorption equipments
- Encapsulation devices and material
Molecular biology
- qPCR : Rotorgene Q (Qiagen)
- PCR : Thermocycler Robocycler Gradient40 (Stratagene) et T3000 Thermocycler (Biometra)
- PFGE : CHEF-DRIII (BioRad)
- System of gel documentationsystem withchemiluminescence image analysis (ChemiDoc XRS, BioRad)
- Microplate reader (SPECTRAmax 340, Molecular devices)
- Fluorescence spectrophotometer
- Agilent 2100 Bioanalyser (Agilent)
Cell culture
- Bioreactors
- 400 ml (Minifor, Lambda Laboratory Instruments)
- 2 L (Labfors, Infors)
- 2 L (Biostat A plus, Sartorius)
- Single-use, 10 – 20 L bags, “wave” agitation (Appliflex I, Applikon Biotechnology)
- Agitation systems for cell culture
- Cellspin, IBS Integra Biosciences
- Cellroll, IBS Integra Biosciences
- Cellspin, IBS Integra Biosciences
- CO2 incubators
- Innova CO-48, Newbrunswick Scientific
- Shellab
- Autoclave (FVA/A1, Fedegari)
- Laminar flow hoods class II (Nuaire)
- Inverse microscope with fluorescence and software for picture acquisition (CKX41, Olympus)
- Ultrapure water system (arium 611VF, Sartorius)
Analytical devices
- Dasgip GA4O2 and CO2 analyser
- Agilent 1100 HPLC
- UV-VIS Spectrophotometers
- Varian Cary Eclipse fluorescence spectrophotometer
- Chemometec Nucleo Counter YC-100 for yeast cell numbering and viability assessment
- Aber Instruments Biomass Monitor